Xisledd
73238
1951
112
https://knowridge.com/2019/11/exposure-to-this-stuff-in-pregnancy-linked-to-high-risk-of-adhd-autism/
If more studies confirm it, this could explain the rise of the two in the past years and maybe even stop some of the stupid anti vac stuff. Either way, this might be huge for prenatal science!!
bigsteve31sk8
I thought it was Fox news.
Someshithead241
ADHD and Autism, oh no? Got one, got a friend with the other. What's the big deal?
foampants
Aw, man. Acetaminophen is pretty much the only thing you are allowed when pregnant for pain relief.
iwouldshootobytwice
25.8% diagnosed with ADHD? That seems so high.
jiynxed
The rise is because we've gotten much better at diagnosing it.
doctorofOT2017
Also in the US we use it to get services covered by insurance. Intellectual disability gets kids nothing but ASD dx gets better resources
Areawoman84
Very scientific to call it "stuff". Fuck these click bait science articles.
iShouldBeWorking42
You can avoid a lot of pain by not having any kids in the first place
rubberbuscuit2018
Crock of Crap!!!The article sites a “study” of 998 babies umbilical cord blood.
Captaintippie
Was told that tylenol was the safe drug to take for all the migraines I got while pregnant.Took it oftenish. None of my kids have any issues
notacobra
Except the rise in autism is linked to improved diagnostic standards and the rise in ADHD curbed in the late 90s.
keenidiot
Not exactly, there's some evidence that's the numbers are more than what we'd expect. But part of its definitely linked to older parents 1
keenidiot
Things like neuro atypical being better able to date, and basically other stuff.
thisonetimeihadakid
If you read the study, there are specific use patterns that resulted in this finding. Very unlikely to blame for any uptick in ADHD
User19
I need to drop knowledge... this study has no control sample and its positives for adhd and Autism are way above average. This is very -
User19
Odd considering tylenol is such a widely used drug.
NoOneLikesYourSelfies
What the fuck! That's what they tell us to take whole pregnant for aches and pains! Fuuuuuuck!
willowed
Yeah I did a lot. Migraines. But my daughter is six and fine.
channelranger
The correlation isn't very strong in this study. Honestly, I'd say this doesn't prove causation at all.
DirkNurple
Yeah I’m on the fence about single studies. There are as many times when it doesn’t cause ADD to make the case for a strong correlation.
joot
This is far from the only study on this topic.
DaveTheScientist
You should never be on the fence about a single study. It's means something might be true, but we're not sure yet. NEVER attribute too much
DaveTheScientist
certainty to a single study. Especially for observational studies.
DirkNurple
I know what things are, Dave!
Xisledd
That's why i definitely thunk there should be more studies, but it's a strong enough correlation to suggest research of causation
HexDarkwood
Would be interesting how they correlate this with the findings adhd is heredity.
aegis27
Epigenetics are frequently implicated in hereditary disorders. There's a reason that a high risk doesn't always equal inevitability.
cardinal29
You know what increased my chances of having ADHD kids? Exposure to my ADHD husband. It's genetic, people!
HFJ13
It’s not all genetic. I have ADHD and no one in my family does.
Kunitsu
could also been a recessive gene in the family noone remembered. hard to tell really, shit pops out of nowhere sometimes it seems
cardinal29
They've all been professionally screened? It presents very differently, and is a spectrum disorder. Plus, denial is high.
HFJ13
My immediate family has. Doctors think it may have been caused by a head injury, but they really don’t know.
helkafen
Careful with epidemiology studies like this one, they need to be replicated. Same thing with "chocolate makes you lose weight!"
helkafen
Key word: "confounding factors". They easily cause statistical correlations and make us believe fake shit.
patapof
Also - is the acetaminophen the cause, or something many people taking acetaminophen have in common. Correlation is not causation; [1/2]
patapof
The article is very careful to call it "association" and implies no causation at this point.
JAPONfan
First they said smoking during pregnancy is bad, then drinking. And now THIS! That's absurd! If not that then why be pregnant?
SuckMahWolleh
There is no clear evidence in this study. there is merely an association, questionable choice of subjects, and no proof of cause and effect
SuckMahWolleh
before going and hollering to all the mothers in the land. Do your research. Look at criticisms of this study - Positive and negative.
NordicusMaximus
Went to ER recently, they ONLY give acetaminophen as a non-narcotic pain reliever, not ibuprofen or naproxen. I only use Advil or Aleve.
DiddlyBits
That's interesting. Aren't some people allergic to acetaminophen? You'd think they'd carry both. Plus acetaminophen is a placebo IMO
cardinal29
I agree. Does nothing for me, it's like drinking a glass of water. No pain or headache relief
PolarBear925
Fun fact: acetominophin is not a vaccine and vaccines don't cause autism.
Cryolith
Unless the general use of acetaminophen has also gone up, in which case it us simoly a confounding factor.
chargeling
https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2753512 That comment by James Little. Makes sense? Aah, I want numbers.
hechicera84
I mean, it’s the only one I was allowed to take while pregnant.
Kunitsu
same here, migraines are a bitch
StepRightUp
So, is Imitrex not allowed for pregnant women? I use it for my migraines & it works really well, but I’ve never been pregnant so, idk.
Kunitsu
from what research i could do in 5min, it appears they havent found any issues with using imitrex while pregnant yet =) always best to talk
Kunitsu
to your doctor first ofc
MastersonWalter
This website is trash. They offer homeopathic cures for ADHD on it. Total garbage.
mystichead
Okay stop, even the paper doesn't give it full causal relationship. Its a freakin cohort level study... Thats not strong methodology
alex5775
Yeah, I was immediately suspicious of the click baity title
dunewolf
its like california and the Prop 65 warnings.. "this item has stuff known in cali to cause cancer" like every goddam thing has it now..
dunewolf
Hell by the logic they put that warning label on things everyone whose gotten cancer has breathed oxygen. OH shit oxygen causes cancer srsly
Nocan
ReptarCrunch
100% of mothers with children having ADHD/Autism drank water and breathed oxygen during pregnancy.
Chereazi
Did they also study the reasons for taking the pain killers? Would be interesting if it could also be factors like complications during
DonaldTrumpsFlaccidHairpiece
Probably a multitude of reasons. i think the fact that this is big is because tylenol has been doctors goto med for pain without BP increase
Dark0001
Its pretty much the only pain med you can take while pregnant - so this study will have had problems getting people who didn't take it
DiddlyBits
This is the failure of most, if not all, human studies. There are WAY too many factors to account for to make any legitimate claim.
Refridgerate
aka an issue with correlational studies. It’s not a failure so much as a limitation, as I’m sure the researchers understood this
DiddlyBits
1/2 I agree that we should still conduct studies, but they'd need to conduct many over a period of decades to be sure.
Goldenbeer
My wife is pregnant now and they don't allow her to take ibuprofen, but recommend tylenol. She gets occasional migraines, rarely takes any.
Leithoa
Ibuprofen & aspirin are blood thinners
Chereazi
pregnancy that are causing pain to the mother that are causing her to take pain meds, making the high levels only symptom and not cause...
toogoodtomiss
Asking good questions!
CrazyEarl
Or something causes pain and autism or ADHD.
HighlandPotatoe
Wtf they essentially measured the level of paracetamol taken close to birth via measuring it in the umbilical cord. The end of pregnancy
HighlandPotatoe
When everything is painful.... And the hospital gives you paracetamol as pain relief. Nothing about taking through rest of pregnancy.
iwouldshootobytwice
Ya this is really weird. I wish these stupid articles would at least cite the original paper so we can see the real data and info
doctorofOT2017
Agreed. Here is the actual article https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2753512
kualityE
Thanks both my kids have autism. Not sure if this was a factor in pregnancy but I wonder if giving it to them as an infant did
iwouldshootobytwice
Only 32.8% were considered neurotypical? That’s insane
hechicera84
I was going to start looking through my universities library ... thanks
electrifyingcosplay
Tylenol is one of the only OTC pain relievers pregnant women are able to use.
noxdracoria
Its still recommended to use it sparingly if at all as they honestly don't know the full effect of any OTC drugs on a developing fetus
CorgiWithAJetPack
This.
Tohob
anti vaxx moms out here blaming vaccinations for high rates of autism in kids when really it's cuz they can't stop popping tylenol, nice.
wombatmcgee
Though they share some symptoms, ADHD and autism are separate disorders.
insulticator
As a mom and a scientist I took tylenol almost every day because my doc said it was fine and pregnancy hurts.
minipancho94
i mean IIRC the rate is like 1 in 10. though its such a broad spectrum we were missing a lot, and you cant spot most high functioning. 1/2
minipancho94
i mean aside from being socially retarded in middle school and still being a bit eccentric now, you'd never tell with me. 2/2
Qualtagh
This isn't a reason to shame people for taking medicines their doctor recommends. I know you're aiming at asshole antivaxxers, but I bet 1/2
Qualtagh
sane moms will feel guilty over this kind of thing, too. 2/2
Kunitsu
hell i took tylenol while pregnant. i got, and still get migraines pretty easily. was the only thing i was allowed to take while
Kunitsu
breastfeeding too. fucking sucked cause it barely took the edge off the pain if i was lucky, and i was super careful about the dose too
Blackcat85
That’s brutal . What can women take during pregnancy? Your whole body hates you for 9 months .
MBdub210
Ummm no. Pregnancy doesn’t suck. Your body doesn’t hate you. It just does what it does. What on earth have you heard, dude?
Blackcat85
I meant no offense. Some women I know have aches & pain , swelling feet etc . They love being preggo , but it takes a toll .
katzenhexe
Pregnancy absolutely does suck sometimes. Just because your body is doing what it needs to do doesn't mean it's always a good time.
MBdub210
Wow. I hope things get/got better for you.
katzenhexe
Pretty much LOL. I can't eat deli meats, can't clean cat litter boxes, can't take Advil and I guess tylenol now. Pregnancy sucks.
MBdub210
Wow. Didn’t realize your life revolved around those things ...such sacrifice.
BoulevardOfBrokenTetris
Why deli meats?
Kunitsu
its because they are kept chilled and can habor bacteria. so unless your heating them up past a 170 ( i think it is) then they arent
Kunitsu
recommended for pregnant women as the risk of getting sick from it is higher
patapof
Knowridge is as trustworthy as your next-door neighbor - here's link to the original article [1/2
Cuzinsam
Chinese. Knowledge report.
patapof
https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2753512 (and guys, learn to distinguish trustworthy sources)
loyjoy
Currently pregnant, almost used paracetemol every day due to my migraines and daily headaches. Will let you guys know how the kid turns out
bigassdolphin
How about you just don't vaccinate and let us know if he/she dies?
sykotic1189
Mine is due any day now and the gf has been taking tylenol almost daily. I'll add our data to yours
loyjoy
Oh good luck! Wishing a fast and easy delivery!
mrsforfunsies
24 weeks along here - only taken 3-4 Tylenol so far but husband is super ADHD. Thinking it’s a forgone conclusion.
loyjoy
I seriously don’t know what to expect either. Husband has mild ADD and high functioning autism which I think it’s social anxiety not autism
kawkamawaq
There is also a strong genetic connection to ADHD. https://scholar.google.ca/scholar?q=adhd+genetic+markers&hl=en&as_sdt=0&as_vis=1&oi=schol
wompwompwomp
Aye. My mom is possibly worse than me and neither of us grew out of it. I share depression with most of my family too
BunchaCrunchOfHuman
Ditto. My guy is 19mo and I wonder about the possibility of this diagnosis on the horizon. But Dad and I are very focused ppl?
NotEven0nce
1 year and 7 months. It's not been repeated yet, so I wouldn't worry until more than one source verifies the findings.
TRDirty
Its strongly hereditary. I had it. My mom had it. Her dad had it. My son has it
ChelsTehHazelnut
Same, but no kids yet. Both parents have it, so do I.
minipancho94
autism is a very broad spectrum as it turns out. im autistic, and getting ready for medschool. was/am socially retarded, but learned, 1/2
minipancho94
though middleschool was hell. also about 1 in 10 are autistic IIRC. my only 2 tips are encourage any interest fully, and be ready to 2/3
minipancho94
deviate from standard systems. look into independent study, early college etc. also encourage hobbies, especially its a weakness 3/3
StepRightUp
Well, I’m not autistic and middle school was hell. So, I mean, you’re totally normal in that regard at least. Congrats on med school, btw!
belly0621
I used it daily for chronic pain when I was pregnant, my sons 11 yo and healthy no developmental issues.
The2020ElectionWasStolen
Until he turns into, literally, Hitler ( j/k)
JudgeMentaI
tune in in 15 years for an update
Beitrix
I used Tylenol a lot in 1st for migraine, didn't help AT ALL so I've just lived in constant pain since. Ready to evict the kid any day now!
nevertrustawetfart
My wife had it had the first 3 months and took a little ... She did the best she could to only use some for like 3 days
HealerwithaGreatsword
Already can't take advil, what are pregnant women supposed to do? Just suffer more?
GlassPHLEGM
.
loyjoy
My doctor actually allows my NSAID now during second trimester. I think it’s best you talk to your doctor if you ned any painkillers
Dontcaredeadinside
The only thing that helped my headaches was caffeine.
SeairaSC
They have told me to avoid caffeine..
DGummibuns
Doot
porcelainfrankenstein
My mother used parecetamol every day when she was pregnant and now i have autism (Asperger). Super fun!
porcelainfrankenstein
But i probably got it from my dad's side of the family
CycloneSP
just remember 'increased' does not mean 'guaranteed' if a chance goes from 2% to 10%, there's still a 90% chance the kid comes out fine
MintMission
it's probably closer to 0.1% -> 0.2%
BoredCreep
That's still an increase from 1 in 50 to 1 in 10 kids though.
AncientSeraph
They're also arbitrary numbers, so don't let that influence you.
BoredCreep
Yeah, I get that. I was just pointing out that even a 'small' increase still has a significant impact on people.
BlackavarLion
You are cutting their legs out from under them. They won't be able to stand to look at you.
TezuNii
The NHS's advice on paracetemol: https://www.nhs.uk/common-health-questions/pregnancy/can-i-take-paracetamol-when-i-am-pregnant/
wtforero
As a father that uses it regularly, my daughter is ok at 5. Anecdotal, at this point, but she’s ahead of the curve according to teachers.
CrazyEarl
If it were a strong or high correlation it would have been discovered by now.
Elnauriel
True, but like many things biological, there's usual a combination of factors working together. This could be a piece of the combination.
chargeling
I'm no statistician, but… an increase by a factor of 2 from low to high exposure does sound like a strong correlation. (95% CI is meh tho…)
branpace
Found a lot of inconclusive research. Thought this was interesting though. https://pediatrics.aappublications.org/content/140/5/e20163840
jedionslaught
Another alternative is thalidomide, as it treats the morning sickness and nausea. It also causes your children to be special /s
StepRightUp
Nope. Not true. They fixed the chemistry error causing that. (A great lesson in chiral chemistry, btw! Google it. Fascinating stuff.)
Kunitsu
try a hot rice pack, i suffer from migraines and the moist heat helped alot. throw uncooked long grain white rice in a large knee sock and
Kunitsu
tie it off (dont over stuff it, you want it semi-soft) toss it in the microwave for 2-4min, wrap in a hand towel and go nap with it on your
Kunitsu
head. its helped me tons not only with migraines but cramps, back aches, sore breasts after feeding... and its cheap to make
loyjoy
I tried everything! Unfortunately nothing works for me. I have migraine with aura and every time the aura changes so I can’t even catch it
Kunitsu
oh god hun i pity you. i hope you eventually find something that helps! im out of ideas =S
doggobell
.
Snooj
Does that mean each day you almost used it each day but ultimately did not use it or that you used it almost every day of the pregnancy?
loyjoy
I’m almost using it every day.
loyjoy
3 years later: Kiddo is almost 2.5 we suspect sensory processing disorder and autism. We have an evaluation in 3 weeks. FML.
Spice002
For those who don't know, Acetaminophen is the generic name for Tylenol, an off the shelf pain killer.
NachoPete
It's also a pretty good song.
dparsons4205772
I think we all knew that bud
SlappedStupid
No? Tylenol is an American brand. I had heard of it, at some point, on American tv (maybe Scrubs), but had no idea what it is.
dparsons4205772
Ya true. You guys call it paracetamol
sexycutepopulartoboot
Thank you!
Awe2Dee2
Well that explains alot actually. Thanks!
BrokenMegaman
I was about to ask What is it in?!
talldean
Its also tied to asthma in some studies.
OGcreek
Lol duh
RavenInFlyte4ever
It's the only pain reliever my doctor would let me take when I had migraines during pregnancy
RavenInFlyte4ever
My son doesn't have ADHD from it. So not everyone will be affected that way
jenniii
Aren't you not supposed to take any pain killers when you're pregnant
HatinS8N
This has been proven to be false. Tylenol is the only thing a patient can take while pregnant. Of course it looks like it but it’s not
Spice002
"Active ingredient (in each tablet) Acetaminophen 325 mg" From https://www.tylenol.com/products/tylenol-regular-strength-tablets#ingredients
HatinS8N
correlation does not mean causation
AlphaKenneyBody
Lots of times it’s added to both oxycodone and hydrocodone.
betterave
Coanalgesia
Telharmonius
Tylenol and its ilk are NOT recommended for small kids, unless *strictly* supervised and proper dosage followed to the letter. Seriously.
ME2G
I always gave have dosage. My mom is a former Ped nurse. She always preferred I use ibuprofen for pain relief.
FayeWillow
Do you have any more in this? I give it to my teething kids and always thought it was fine!
kualityE
We would only give it at night and try to deal with it during the day to try and limit its use
Telharmonius
Tylenol is hell on the liver. But the liver is good at recovering from small hits. If people overdose on T, it can't keep up. Many docs 1/2
FayeWillow
Thank you!
Telharmonius
2/2 are wary of recommending it to parents who're likely NOT to follow the dosage. No drug is 100% safe. They are safest when used properly.
Nursedaisy
Basically the only medication women have been told is safe in pregnancy...
Reofrax
well ADHD isnt all that bad. look at me, i turned out just fine. Rough childhood though
ZombieJonSnow
I bet you made a fortune selling adderall.
Reofrax
Adderall didnt work for me so never got more than the 3 day trial doses.
ZombieJonSnow
Damn, the only benefit stolen away.
OfficalFloridaWoman
The docs reccomend the tylenol during pregnancy. It's a conspiracy!
PuppersArtAndScience
So what you're telling me is pregnancy sucks
Sutashi
I think you can have a little wine. That may help.
Anynonmoose
Also a leading cause of liver failure. Acetaminophen is nasty stuff. It should be prescription only.
TheRockDude
You can't just say anything with side effects should be prescription only. Do you really want to schedule a doctor's visit every time -
TheRockDude
- you've got like a headache or slight fever?
TheRockDude
Also, pharmacy wait times would probably triple, which would be an enormous pain for people who need maintenance drugs
schizznatt
There are lots of people who can't take NSAIDs (ibuprofen, aspirin etc) so acetaminophen is the only OTC alternative for them
thesashachronicles
It’s very safe when taken in reasonable amounts, assuming your liver is in good shape. Same reason why it’s safe to have one to two drinks—
thesashachronicles
per night, because your liver is able to completely metabolize it. The misuse/overdose of acetaminophen is a leading cause of liver failure.
Anynonmoose
you have a headache and you take 2. Two hours later, your head still hurts. You dont know the dangers because it's not labeled. You take>
Anynonmoose
Two more. Repeat this until headache goes away. You die. Thanks tylenol.
BoringSeattleite
AKA Paracetamol in the UK
valen00
Australia too
ItIsByWillAloneISetMyMindInMotion
Specifically that is the drug name, not the common brand name in the UK.
Daeviews
I always wondered what tylenol was
Daeviews
I'm kiwi. Its paracetamol here too
DramaticInternetNonsense
Thanks
betterave
And the rest of Europe too. Or just Europe. Whatever.
PurplePickleEater
It's also the alternative to ibuprofen, which you aren't supposed to take while preggers. So now we get no painkillers, I guess...
WellBehavedZombie
https://www.drugs.com/acetaminophen.html It's in Vicks, and a whole bunch of random non-prescription meds.
AlphaKenneyBody
Kratom
Nursedaisy
Exactly
FineNevermind
Epidural for a few months will do good.
YeOldeImgurian
As ones wiser than me once said, the Power Rangers, "It's Morphin' Time!" (Hint: the apostrophe is an "e")
Leonezia
You get nothing while pregnant. Only pain and sorrow like good ol medicine
kerms
If your pain only requires an off the shelf painkiller then you can tough it out for the sake of the baby.
CatatonicCowMoo
Eh fuck it. We'll just start handing out heroin to pregnant ladies.
tooomanystevesgotbanned
What about paracetamol? Codeine?
Nurich
Codeine has often also alcohol in it so noooope
Nurich
Oh and the post is about paracetamol
idontfinishmysentences
What about crack? Like maybe one or two though?
illtakethingsthatneverhappenedfor200alex
Raspers
Just a little bit of crack
PurplePickleEater
Only in moderation
Mayonnaiseisainstrument
Crack seems ok to me
truemetalman
What about Naproxin or good old Aspirin?
lookingforapurpose
Naproxen is ibuprofen. Aspirin thins your blood which can trigger a miscarriage.
Nursedaisy
All are nope
PurplePickleEater
Neither is recommended. Both can cause premature birth under certain circumstances.
ElChupaNuggra
Marijuana! Marijuana! Marijuana! Marijuana! Marijuana! Though I doubt it has NO side effects for developing infants so... maybe?
Anynonmoose
Blood thinners.
nrpaladin
Technically no. Anti-platelet action does not mean blood thinner. Just prevents aggregation of platelets to already formed clots etc
blackrasputin
Those are both NSAIDs which you’re not supposed to take. who knew gulping down pain killers wasn’t such a great idea?
TheRockDude
What about cocaine?
reverendbonobo
It won't lead to autism, but it will lead to more cocaine.
iShouldBeWorking42
Do you want your baby to be born an 80s business guy? Because that’s how you get your baby to be born an 80s business guy.
Jokesterwild
Truth. My wife was told not to take anything while she was pregnant. Idk if that's just in Canada or common in other places.
jinjaneko
Canadian, and I was told the same. There was a lot of 'don't, just in case'. Really sucked.
Jokesterwild
yeah thats what we noticed. I mean I get it. but boy is that list long.
HFJ13
I had a baby in January and I was told I could take Tylenol sparingly.
PurplePickleEater
I'm pregnant now and that's what I was told too. Luckily, I guess, Tylenol doesn't work for me so I haven't taken any.
[deleted]
[deleted]
Nursedaisy
The social workers are not big fans of that natural remedy.
SpecialProjectY
Even during pregnancy?
theDogter
Help with pain, and sickness, and some of the stress. I wonder how much would pass through to the child?
ScipioWright
Especially as a guy during pregnancy
MiasmaCorrigan
I've heard of women smoking to encourage appetite and possibly reduce pain? I think more studies could be done on that honestly.
SpicyaMeatball
My friend had two kids and both have learning disabilities. She openly admitted to burning during pregnancy. Connection? Maybe.
nerdasaursaysrawr
There is very little data on the effects of marijuana on a fetus but most of what does exist recommends no weed.