ShadeWilson2

10220 pts ยท May 15, 2015


If you're looking at this, we're probably arguing on the internet... I'll argue with a helium balloon about which way is up, so I guess settle in.

It's also, enormously, the media ecosystem. What's permissible, right, wrong, good, bad, tough, weak, up, down, blue, red, inside or out is so enormously shaped by the media it's hard to understand the scope of it.

5 months ago | Likes 23 Dislikes 1

She's doing the only thing she can to try to be relevant - react. Towing the company line will leave her fading into the background. She needs to be outraged by something in order to "matter". Notice she's not saying "We need to do X, Y or Z to help regular people." She's just saying "I'm outraged by this and you should be too" with nothing productive to offer. It's reactionary politics, like the vast majority of conservatives. It's not new behavior.

5 months ago | Likes 1 Dislikes 0

#2 Keaton Henson is such an unbelievably beautiful song writer; it almost feels like a dream. I couldn't listen to his music for years after some life happened and I'm just starting to again this last week. Strange to see it in the wild internet.

6 months ago | Likes 2 Dislikes 0

Businesses have been trying to automate away having employees for years: an empowered human who could help you got replaced by a call centre got replaced by a phone tree got replaced by an online portal and now is getting replaced by AI.
The actual human with the authority to help you on the phone was the quickest and most helpful for the customer, but it's the most expensive for the business.
AI is just a better tool to do a shittier job than an actual human could do.

6 months ago | Likes 11 Dislikes 0

Sugar does actually act on opioid and dopamine receptors... But it does not function like a stimulant.. cocaine is a stimulant.. stimulants are serotonin "boosters"... Does this person mean seratonin in the CNS? GI? Systemically? All with vastly different effects. This post is a mess.

Please people, have the perspective to know you don't understand a thing. We do not have to be experts in every single arena of human knowledge just because we have access to it.

6 months ago | Likes 2 Dislikes 0

#31 Does the line "He shoot coca cola" answer your question?

7 months ago | Likes 3 Dislikes 0

And your comment is surely be exactly the help she may or may not need. If help was needed, then a stranger on the internet shaming her is exactly the signpost on the road to healing she might need.
This is sarcasm.
Your comment is useless, harmful, and cruel.
You've added nothing to this but a high five zone for other people who want to be mean in the same way.
Disgusting.

8 months ago | Likes 29 Dislikes 3

It's also supposed to be our government's job: government is really meant to be a union of all its citizens, where a billionaire voice holds only as much weight as a janitor's or a teacher's or anyone else's.
Minimum wages, employment law, worker protections, tax funded public services (including healthcare, education, etc), social safety nets, and on and on and on. These things all serve to move money from the wealthy to the rest of us.
Money in politics has corrupted this.

8 months ago | Likes 2 Dislikes 0

We have an entire system of being that rewards that, unfortunately.

8 months ago | Likes 11 Dislikes 0

Even with allll the other criticisms, I wish business owners and middle class capitalists would figure out that when conservatives say they are "business friendly" or " the economy" they don't mean your business or your economy.

They're in power to serve their multi-million dollar donors. The priority of those donors is to drain your business and drain the middle and working class and drain the government to line their own coffers.

They want you to fail because it makes the rich richer.

8 months ago | Likes 3 Dislikes 0

All of this is to say that anyone is vulnerable to this way of thinking with the right environment and upbringing.
And mostly the only way to get them to actually change is to give them a worthwhile in-group to subscribe to that doesn't believe all this hateful nonsense.

8 months ago | Likes 2 Dislikes 0

All of this truly heinous shit is not a coherent philosophy they've reached by critically examining these issues and then deciding what their stance is - it's all just in-group signalling and identity forming. If you want the first bump from the guy sitting next to you on the pew, you gotta scream that the gays are going to hell and abortion is murder just as loud. It's why they hold onto these things despite all evidence and reason, and it's why they shift every time the dear leader says so.

8 months ago | Likes 3 Dislikes 0

I mean, that's not ALL you could do.

9 months ago | Likes 6 Dislikes 0

You've stated something that is literally being done (though not successfully yet) in the research you linked is impossible: differentiating of new beta cells from stem cells and implantation of them somewhere other than the islet of Langerhans in the pancreas. When this was pointed out your rebuttal was: "Okay yeah but they haven't made it work yet."
If you're a 20+ year expert in this, it very much has not come across in your comments.

9 months ago | Likes 1 Dislikes 0

Your argument so far has been "I say it's impossible" followed by "The researchers literally trying to solve the problem I said was impossible haven't solved it yet and therefore it's impossible." And now an argument from authority.
You've demonstrated a misunderstanding of how beta Langerhans cells work "If you had too many you'd have an insulin overdose" as any amount of these cells do not overproduce insulin except in specific disease processes such as those resulting in adrenal crisis.

9 months ago | Likes 1 Dislikes 0

And you are asserting that there is no and will never be any way to overcome that because you have some kind of omniscient knowledge of present and future that allows you to understand every single possible outcome of this research?
This was literally being touted as a breakthrough. The whole definition of a breakthrough is now being able to do something that wasn't possible before.
Put your Google expertise to bed and move on man.

9 months ago | Likes 1 Dislikes 0

The first few paragraphs of this article literally say they are producing new insulin producing cells by differentiating them from stem cells and then implanting them where they do not normally exist in the body (the liver in this case).

9 months ago | Likes 1 Dislikes 0

And while yes, flooding someone with extra insulin they don't need is extremely dangerous, that's exactly what endogenous insulin producing cells do not do, as they essentially switch off when they have released the right amount.
Insulin resistance results in the existing beta cells to be unable to keep up with the need for insulin in insulin dependant type 2 diabetics.

9 months ago | Likes 1 Dislikes 0

Unless I'm misunderstanding, insulin producing cells release insulin in response to their environment, and to hormone signals. The presence of more cells would then release more insulin, as there are more cells being signaled at a given moment.
Insulin resistance reduces the cell response to insulin, thus preventing glucose from moving from the extracellular environment to intracellular. High extracellular glucose is the primary signal releasing insulin.

9 months ago | Likes 1 Dislikes 0

I'm just guessing here as this isn't my area of expertise but I think you answered your own question. More insulin producing tissues producing more insulin to supplant the need for supplementation through injection.

9 months ago | Likes 1 Dislikes 0

The article itself clearly states they have treated both a type 1 and type 2 diabetic. Some type 2 diabetics, typically more severe cases, do become insulin dependent.
You are correct that this apparent treatment does nothing to address insulin resistance.
A more correct language would have been "a potential cure for insulin dependant diabetes (IDDM)."

9 months ago | Likes 9 Dislikes 0

Oh look, someone who doesn't understand subtext, satire, or political commentary.
You can dislike Starship Troopers as a personal taste, but to say it's "a terrible movie" is demonstrably false by every metric of how we judge art and cinema. Just as in RoboCop, the "bad" is deliberate commentary, and it absolutely works. It's satire.

9 months ago | Likes 12 Dislikes 1

Christian fundamentalists.

9 months ago | Likes 3 Dislikes 0

#10 Do we need to tell the Americans about No Name?

9 months ago | Likes 3 Dislikes 0

I work in healthcare. While some slip through, 99.8% of the time we stop anyone in the profession from doing terrible things. It makes international news when a single healthcare worker does wrong.
Other people in positions of public trust are batting 998 while Christians are batting 300.
Denouncing isn't strong enough.

9 months ago | Likes 5 Dislikes 0

I say this with as much grace as I can muster: these people are fucking idiots.

9 months ago | Likes 2 Dislikes 0

I also don't think anyone in their right mind builds a road so (apparently) close to the water what with, like.. erosion. There's no bank down to the water in this image.

9 months ago | Likes 6 Dislikes 2

$800,000,000 poorer as a community is where you are.

9 months ago | Likes 7 Dislikes 0